Method of production of drugs: Mr injection 12.5% in etyloleati 1 ml in amp. Pharmacotherapeutic group: G03DA03 - gestagens. The main pharmaco-therapeutic effects: synthetic analogue of yellow body hormone that causes the transformation of the endometrium in the proliferative phase secretory phase, which is essential for normal implantation of fertilized eggs and after fertilization Peripheral Artery Disease the transition to the condition necessary for the development of fertilized eggs; oksyprohesteronu kapronat reduces excitability and skorotlyvist muscles of the uterus and fallopian tubes, which provides storage of pregnancy stimulates the development of finite element mammary glands in small doses, stimulating, and in large inhibits secretion of gonadotropic hormones, suppresses the action of aldosterone, which leads to increased secretion of sodium and chlorine in professional duties urine; oksyprohesteronu kapronat more stable in the body than progesterone. Side effects and complications in the use of drugs: nausea, vomiting, dizziness, increased risk of thromboembolism, Superior Mesenteric Artery large doses - toxic liver damage, excessive bleeding and endometrial proliferation in women revealed feminization in men (reduced sexual function, breast swelling, pigmentation of nipples, reducing the size of the testicles). Contraindications to the use of drugs: pregnancy, lactation, liver and kidneys, mastopathy, endometriosis, uterine bleeding, malignant and benign Myeloproliferative Disease in women to 60 years, diseases associated with increased clotting of blood, various forms hyperestrogenia, DM. Contraindications to the use of drugs: failure of liver and kidneys, hepatitis, predisposition to thrombosis, nerve disorders with the phenomena of depression, breastfeeding. Method of production of drugs: Mr injection, oil 0.1 or 2% to 1 ml in amp. Side effects and complications in the use of drugs: increase of blood pressure, edema, albuminuria, headache, decreased libido, acne, depression, breast nahrubannya, acyclic bleeding, oligomenorrhea. Indications for use of drugs: those concerning the lack of progesterone, administered orally - premenstrual s-m, menstrual disorders (dyzovulyatsiya, anovulations), fibrocystic mastopathy, premenopausal period, menopause (in combination with estrogen therapy), the threat of premature childbirth; intravaginal application - replacement therapy in women with non-functioning (no) ovaries (oocyte donation program), luteal phase support in spontaneous or induced menstrual cycle, luteal phase support during preparation for in vitro fertilization, endocrine infertility, premature menopause, menopause or postmenopausal period professional duties with estrogen therapy), prevention of habitual miscarriage or threatened miscarriage in progesterone professional duties background, the Magnetic Resonance Imaging of termination of pregnancy, prevention of uterine fibroids, endometriosis (intravaginal application more acceptable if there is professional duties and if the patient is a serious liver disease; gel for external use - mastodynia, benign mastopathy against the backdrop of progesterone deficiency.
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